Effects of apelin-13 on myocardial ischemia reperfusion injury in streptozotocine induced diabetic rats
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چکیده
منابع مشابه
Protective effects of tanshinone IIA sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
Objective(s): This study investigated the protective effect of tanshinone IIA sodium sulfonate (TSS) on ischemia-reperfusion (I/R) induced cardiac injury, and the underlying mechanism of action. Materials and Methods:Male Sprague-Dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. Half an hour before the left coronary artery ligation, rats were ...
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Introduction: Acute kidney injury (AKI) has been known as a complex clinical complication in diabetic patients. The main cause of AKI is ischemia/reperfusion injury (IRI). This study was designed to investigate the protective effects of GABA on renal IRI in hyperglycemic female and male rats. Methods: Sixty STZ induced diabetic male and female Wistar rats were categorized in 10 groups (5 fem...
متن کاملprotective effects of tanshinone iia sodium sulfonate on ischemia-reperfusion-induced myocardial injury in rats
objective(s): this study investigated the protective effect of tanshinone iia sodium sulfonate (tss) on ischemia-reperfusion (i/r) induced cardiac injury, and the underlying mechanism of action. materials and methods:male sprague-dawley rats were subjected to a 30-min coronary arterial occlusion followed by 24 hours' reperfusion. half an hour before the left coronary artery ligation, rats ...
متن کاملIntermedin protects against myocardial ischemia-reperfusion injury in diabetic rats
BACKGROUND Diabetic patients, through incompletely understood mechanisms, endure exacerbated ischemic heart injury compared to non-diabetic patients. Intermedin (IMD) is a novel calcitonin gene-related peptide (CGRP) superfamily member with established cardiovascular protective effects. However, whether IMD protects against diabetic myocardial ischemia/reperfusion (MI/R) injury is unknown. ME...
متن کاملThe effect of levosimendan on myocardial ischemia-reperfusion injury in streptozotocin-induced diabetic rats.
Objective Ischemia/reperfusion (I/R) injury is an important cause of myocardial damage by means of oxidative, inflammatory, and apoptotic mechanisms. The aim of the present study was to examine the potential cardio protective effects of levosimendan in a diabetic rat model of myocardial I/R injury. Methods A total of 18 streptozotocin-induced diabetic Wistar Albino rats (55 mg/kg) were randomly...
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ژورنال
عنوان ژورنال: Bratislava Medical Journal
سال: 2018
ISSN: 1336-0345
DOI: 10.4149/bll_2018_065